Publikationen

Reference (authors, title, journal, volume number, pages, year).                               

Link to Pubmed

91. S. Brantl and P. Müller. Cis- and trans-encoded small regulatory RNAs in Bacillus subtilis.                                                                                     Microorganisms 9: 1865 (2021) 

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90. I. Ul Haq, S. Brantl and P. Müller. A new role for SR1 from Bacillus subtilis – regulation of sporulation by inhibition of kinA translation.                            Nucleic Acids Res. 49: 10589-10603 (2021) 

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89. I. Ul Haq and S. Brantl. Moonlighting in Bacillus subtilis: The small proteins SR1P and SR7P regulate the moonlighting activity of glyceraldehyde 3-phosphate dehydrogenase A (GapA) and enolase in RNA degradation.                 Microorganisms 9: 1046 (2021)                                                                                                                                       

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88. I. Ul Haq, P. Müller, and S. Brantl. SR7 - a dual-function antisense RNA from Bacillus subtilis.
RNA Biol. 16: 104-117 (2021)

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87. I. Ul Haq, P. Müller, and S. Brantl. Intermolecular communication in Bacillus subtilis. RNA-RNA, RNA-protein and small protein-protein interactions.
Front. Mol. Biosci. 7: 178 (2020)

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86. N. Kubatova, D. J. Pyper, H. R. A. Jonker, K. Saxena, L. Remmel, C. Richter, S. Brantl, E. Evguenieva-Hackenberg, W. Hess, G. Klug, A.   Marchfelder, J. Soppa, W. Streit, M. Mayzel, V. Y. Orekhov, M. Fuxreiter, R. Schmitz-Streit and H. Schwalbe. Rapid biophysical characterization and NMR structural analysis of small proteins from bacteria and archaea.                                          Chembiochem. 21: 1178-1187 (2019) 

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85. S. Brantl and P. Müller. Toxin-Antitoxin Systems in Bacillus subtilis.
Toxins (Basel) 11: E262 (2019)

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84. P. Müller, M. Gimpel, T. Wildenhain and S. Brantl. A new role for CsrA: promotion of complex formation between an sRNA and its mRNA target in Bacillus subtilis.
RNA Biol.16: 972-987 (2019)

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83. D.R. Reuß, P. Faßhauer, P. J. Mroch, I. Ul Haq, B. M. Koo, A. Pöhlein, C. A. Gross, R. Daniel, S. Brantl and J. Stülke.
Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis.
Nucleic Acids Res. 4: 5231-5242 (2019)

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81. M. Dormeyer, A. L. Lübke, P. Müller, S. Lentes, D. R. Reuß, A. Thürmer, J. Stülke, R. Daniel, S. Brantl and F. M. Commichau. Hierarchical mutational events compensate for glutamate auxotrophy of a Bacillus subitlis gltC mutant.     Environ. Microbiol. Rep. 9: 279-289 (2017)                                                        

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80. M. Gimpel, C. Maiwald, C. Wiedemann, M. Görlach and S. Brantl. Characterization of the interaction between the small RNA-encoded peptide SR1P and GapA from Bacillus subtilis.
Microbiology 163: 1248-1259 (2017)

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79. M. Gimpel and S. Brantl. Dual-function small regulatory RNAs in bacteria. Invited MicroReview
Mol. Microbiol. 103: 387-397 (2017)

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78. E. Grohmann, N. Goessweiner-Mohr and S. Brantl. DNA binding proteins regulating pIP501 transfer and replication.                                                               Frontiers in Mol. Biosciences 3: 42 (2016)

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77. M. Gimpel and S. Brantl. Dual-function sRNA encoded peptide SR1P modulates moonlighting activity of B. subtilis GapA.
RNA Biol. 13: 916-926 (2016)

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76. J. Rosenberg, P. Müller, S. Lentes, M. J. Thiele, D. R. Zeigler, D. Tödter, H. Paulus, S. Brantl, J. Stülke and F. M. Commichau. ThrR, a DNA-binding transcription factor involved in controlling threonine biosynthesis in Bacillus subtilis.
Mol. Microbiol. 101: 879-893 (2016)

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75. P. Müller, N. Jahn, C. Ring, C. Maiwald, R. Neubert, C. Meißner and S. Brantl. A multistress responsive type I toxin-antitoxin system: bsrE/SR5 from the B. subtilis chromosome.
RNA Biol. 13: 511-523 (2016)

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74. N. Jahn and S. Brantl. Heat-shock-induced refolding entails rapid degradation of bsrG toxin mRNA by RNases Y and J1.                               Microbiology 162: 590-599 (2016)

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73. C. Meißner, N. Jahn and S. Brantl. In vitro characterization of the type I toxin-antitoxin system bsrE/SR5 from Bacillus subtilis.                                         J. Biol. Chem. 291: 560-571 (2016)

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72. N. Jahn, S. Brantl and H. Strahl. Against the mainstream: the membrane-associated type I toxin BsrG from Bacillussubtilis interferes with cell envelope biosynthesis without increasing membrane permeability.
Mol. Microbiol. 98: 651-666 (2015) 

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71. H. Krügel, K. M. Klimina, G. Mrotzek, A. Tretyakov, G.  Schöfl, H. P. Saluz, S. Brantl, E. U. Poluektova, V. N. Danilenko. Expression of the toxin-antitoxin genes yefM_Lrh, yoeB_Lrh in human Lactobacillus rhamnosus isolates.
J. Basic Microbiol. 55: 982-991(2015)

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70. S. Brantl and N. Jahn. sRNAs in bacterial type I and type III toxin-antitoxin systems.
FEMS Microbiol. Rev. 39: 413-427 (2015)

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69. S. Brantl. Antisense-RNA mediated control of plasmid replication – pIP501 revisited.
Plasmid 78: 4-16 (2015)

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68. S. Brantl and R. Brückner. Small regulatory RNAs from low-GC Gram-positive bacteria.
RNA Biol. 11: 443-456 (2014)

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67. S. Brantl. Plasmid replication control by antisense RNAs.
Microbiol. Spectr. 2(4), doi:10.1128/microbiolspec.PLAS-0001-2013 (2014)
Book chapter for "Plasmids: Biology and Impact in Biotechnology and Discovery" ASM Press. Book published May 2015.

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66. N. Jahn and S. Brantl. One antitoxin – two functions: SR4 controls toxin mRNA decay and translation.
Nucleic Acids Res. 41: 9870-9880 (2013)

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65. S. Brantl. Bacterial type I toxin-antitoxin systems.                                         RNA Biol. 9: 1488-1490 (2012)

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64. S. Durand, N. Jahn, C. Condon, and S. Brantl. Type I toxin-antitoxin systems in Bacillus subtilis.
RNA Biol. 9: 1491-1497 (2012)

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63. M. Gimpel, H. Preis, E. Barth, L. Gramzow and S. Brantl. SR1 – a small RNA with two remarkably conserved functions.                                                     Nucleic Acids Res. 40: 11659-11672 (2012) 

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62. M. Gimpel and S. Brantl. Construction of a modular plasmid family for chromosomal integration in Bacillus subtilis.
J. Microbiol. Methods 91: 312-317 (2012)

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61. S. Brantl. Acting antisense: plasmid- and chromosome-encoded sRNAs from Gram-positive bacteria. Invited review for
Future Microbiol. 7: 853-871 (2012)

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60. N. Jahn, H. Preis, C. Wiedemann and S. Brantl. BsrG/SR4 from  Bacillus subtilis – the first temperature-dependent type I toxin-antitoxin system.
Mol. Microbiol. 83: 579-598 (2012)

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59. S. Brantl. Small regulatory RNAs (sRNAs) - key players in prokaryotic metabolism, stress response and virulence.
Regulatory RNAs: Basics, Methods, Applications. Springer Edition. Eds. Bibekanand Mallick, Zhumur Gosh.
Chapter 4, pp. 73-109. Doi 10.1007/978-3-642-22517-8_4 Springer-Verlag Berlin-Heidelberg (Jan. 2012)

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58. A. Licht, P. Freede and S. Brantl. Transcriptional repressor CopR acts by inhibiting RNA polymerase binding.
Microbiology 157: 1000-1008 (2011)

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57. H. Krügel, A. Licht, G. Biedermann, A. Petzold, J. Lassak, Y. Hupfer, B. Schlott, C. Hertweck, M. Platzer, S. Brantl, and H.-P. Saluz. Cervimycin C resistance in Bacillus subtilis is due to a promoter-up mutation and increased mRNA stability of the constitutive ABC-transporter gene bmrA.
FEMS Microbiol. Lett. 313: 155-163 (2010)

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56. S. Brantl. Small non-coding RNA in bacteria.
Chemical Biology of Nucleic Acids. John Wiley and Sons Ltd.Ed. Günther Mayer. Chapter 9, pp. 199-222 (2010)

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55. S. Brantl and A. Licht. Characterisation of Bacillus subtilis transcriptional regulators involved in metabolic processes.
Curr. Protein and Peptide Sci. 11: 274-291 (2010)

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54. M. Gimpel, N. Heidrich, U. Mäder, H. Krügel, and S. Brantl. A dual function sRNA from B. subtilis: SR1 acts as a peptide encoding mRNA on the gapA operon.
Mol. Microbiol. 76: 990-1009 (2010)

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53. A. Licht and S. Brantl. The transcriptional repressor CcpN from Bacillus subtilis uses different repression mechanisms at different promoters.
J. Biol. Chem. 284: 30032-30038 (2009)

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52. R. A. Eckart, S. Brantl, A. Licht. Search for additional targets of the transcriptional regulator CcpN from Bacillus subtilis. 
FEMS Microbiol. Lett. 299: 223-231 (2009)

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51. H. Preis, R. A. Eckart, R. K. Gudipati, N. Heidrich, and S. Brantl. CodY activates transcription of a small RNA in Bacillus subtilis.  
J. Bacteriol. 191: 5446-5457 (2009)

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50. S. Brantl. RNAs, Small.
Chapter for                                                                                                     Encyclopedia of Microbiology. Editor: Moselio Schaechter,  Oxford: Elsevier Science. Pp. 409-438. (April 2009)

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49. S. Brantl. Bacterial chromosome-encoded small regulatory RNAs. 
Future Microbiol. 4: 85-103. (2009)

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48. S. Brantl. Antisense-RNAs. Cis und trans: Genregulation in Bakterien.
BIOspektrum Heft 6 (2008)

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47. Licht, R. Golbik and S. Brantl. Identification of ligands affecting the activity of the transcriptional repressor CcpN from Bacillus subtilis.
J. Mol. Biol. 380: 17-30 (2008)

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46. C. Geist and S. Brantl. TraM protein of plasmid R1: In vitro selection of the target region reveals two consensus 7 bp binding motifs spaced by a 4 bp linker of defined sequence.
Plasmid 59: 20-35. (2008)

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45. S. Brantl. Metal sensing by RNA in bacteria: Exception or Rule.
ACS Chem Biol. 2: 656-660 (2007)

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44. N. Heidrich, Moll I., and S. Brantl. In vitro analysis of the interaction between the small RNA SR1 and its primary target ahrC mRNA.
Nucleic Acids Res. 35: 4331-4346 (2007)

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43. T. Waldminghaus, N. Heidrich, S. Brantl, and F. Narberhaus. FourU: A novel type of RNA thermometer in Salmonella.
Mol. Microbiol. 65,:413-424 (2007)

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42. S. Brantl Regulatory mechanisms employed by cis-encoded antisense RNAs.
Curr. Op. Microbiol. 10: 102-109 (2007)

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41. N. Heidrich and S. Brantl. Antisense-RNA mediated transcriptional attenuation in plasmid pIP501: The simultaneous interaction between two complementary loop pairs is required for efficient inhibition by the antisense RNA.
Microbiology 153: 420-427 (2007)

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40. Licht and S. Brantl. Transcriptional repressor CcpN from Bacillus subtilis compensates asymmetric contact distribution by cooperative binding.
J. Mol. Biol. 364: 434-448 (2006).

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39. N. Heidrich, A. Chinali, U. Gerth and S. Brantl. The small untranslated RNA SR1 from the B. subtilis genome is involved in the regulation of arginine catabolism.
Mol. Microbiol. 62: 520-536 (2006)

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38. S. Brantl. Bacterial gene regulation: Metal ion sensing by proteins or RNA.
Trends Biotechnol. 24: 383-386 (2006)

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37. Licht, S. Preis and S. Brantl. Implication of CcpN in the regulation of a novel untranslated RNA (SR1) in Bacillus subtilis.
Mol. Microbiol. 58: 189-206 (2005)

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36. S. Brantl. Bacterial gene regulation: From transcription attenuation to riboswitches and ribozymes.
Trends Microbiol. 12: 473-475 (2004)

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35. P. Freede and S. Brantl. Transcriptional repressor CopR: Use of SELEX to study the copR operator indicates that evolution was directed at maximal binding efficiency.
J. Bacteriol. 186: 6254-6264 (2004)

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34. S. Brantl. Plasmid replication controlled by antisense RNAs.
Invited review for Section 1 in "The Biology of Plasmids". Chapter 3: S. 47-62. ASM press. Editors: B. Funnell and G. Phillips  (2004)

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33. N. Heidrich and S. Brantl. Antisense-RNA mediated Transcriptional Attenuation: Importance of a U-turn loop Structure in the Target RNA of Plasmid pIP501 for Efficient Inhibition by the Antisense-RNA.
J. Mol. Biol. 333: 917-929 (2003)

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32. K. Steinmetzer, B. Behlke, M. Lorenz, P. Freede and S. Brantl. CopR Binds and Bends ist target DNA: Structure and Sequence of the DNA in the CopR-DNA complex. (Meeting Abstracts: Plasmid Biology 2002, International Symposium on Molecular Biology of bacterial plasmids).
Plasmid 48: 237 (2002)

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30. K. Steinmetzer, K. Kuhn, J. Behlke, R. Golbik and S. Brantl. Plasmid pIP501 encoded transcriptional repressor CopR: single amino acids involved in dimerization are also important for folding of the monomer.
Plasmid 47: 201-209 (2002)

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29. S. Brantl. Antisense-RNA regulation and RNA interference.
Bioch. Biophys. Acta 1575: 15-25 (2002)

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28. K. Steinmetzer, J. Behlke, S. Brantl and M. Lorenz. CopR binds and bends its target DNA: A footprinting and fluorescence resonance energy transfer study.
Nucleic Acids Res. 30: 2052-2060 (2002)

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27. S. Brantl and E. G. H. Wagner. An antisense RNA-mediated transcriptional attenuation mechanism functions in Escherichia coli.
J. Bacteriol. 184: 2740-2747 (2002) 

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26. K. Kuhn, K. Steinmetzer and S. Brantl. Transcriptional repressor CopR: dissection of stabilizing motifs within the C terminus.
Microbiology 147: 3387-3392 (2001)

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25. K. Steinmetzer, A. Hillisch, J. Behlke, S. Brantl.  Plasmid pIP501 encoded transcriptional repressor CopR: The acidic C terminus is not required for DNA binding and dimerization, but for protein stability.
Plasmid 45: 138 (2001) (Meeting Abstracts: Plasmid Biology 2000, International Symposium on Molecular Biology of bacterial plasmids)

24. K. Kuhn, K. Steinmetzer, and S. Brantl. Transcriptional repressor CopR: The structured acidic C-terminus is important for protein stability.
J. Mol. Biol.  300: 1021-1031 (2000) 

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23. S. Brantl and E. G. H. Wagner. Antisense RNA-mediated transcriptional attenuation - an in vitro  study of plasmid pT181.
Mol. Microbiol. 35: 1469-1482 (2000) 

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22. K. Steinmetzer, A. Hillisch, J. Behlke, and S. Brantl. Transcriptional repressor CopR: Amino acids involved in forming the dimeric interface.
PROTEINS: Structure, Function and Genetics 39, 408-416 (2000)

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21. K. Steinmetzer, A. Hillisch, J. Behlke, and S. Brantl. Transcriptional repressor CopR: Structure model based localization of the deoxyribonucleic acid binding motif.
PROTEINS: Structure, Function and Genetics. 38: 393-406 (2000) 

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20. K. Steinmetzer, J. Behlke and S. Brantl. Biochemical characterization of the pIP501 encoded transcriptional repressor CopR.
Plasmid 41: 170 (1999) (Meeting Abstracts: Plasmid Biology 98, International Symposium on Plasmid Biology.) 

19. S. Brantl. Antisense-RNA-vermittelte Genregulation bei Bakterien.
BIOspektrum Heft 1: 27-30. (1999)

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18. E. G. H. Wagner and S. Brantl. Kissing and RNA stability in antisense control of plasmid replication.
TIBS 23: 451-454 (1998) 

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17. S. Brantl and E. G. H. Wagner. Antisense-RNA mediated replication control: a comparison between plasmids pIP501 and pT181.
Biol. Chem. 379. Special Supplement p.54 (1998)

16. K. Steinmetzer, J. Behlke and S. Brantl. Plasmid pIP501 encoded transcriptional repressor CopR binds to its target DNA as a dimer.
J. Mol. Biol. 283: 595-603 (1998)

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15. S. Brantl and E. G. H. Wagner. Dual function of the copR gene product of plasmid pIP501.
J. Bacteriol. 179: 7016-7024 (1997) 

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14. K. Steinmetzer and S. Brantl. Plasmid pIP501 encoded transcriptional repressor CopR binds asymmetrically at two consecutive major grooves of the DNA.
J. Mol. Biol. 269: 684-693 (1997)

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13. S. Brantl, and E. G. H. Wagner. An Unusually Long-lived Antisense RNA in Plasmid Copy Number Control: in vivo RNAs Encoded by the Streptococccal Plasmid pIP501.
J. Mol. Biol. 255: 275-288 (1996)

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12. S. Brantl. The copR gene product of plasmid pIP501 acts as a transcriptional repressor at the essential repRpromoter.
Mol. Microbiol. 14: 473-483 (1994)

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11. S. Brantl and E. G. H. Wagner. Antisense RNA-mediated transcriptional attenuation occurs faster than stable antisense/target RNA pairing - an in vitro study of plasmid pIP501.
EMBO J. 13: 3599-3607 (1994)

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10. S. Brantl, C. Kummer and D. Behnke. Complete nucleotide sequence of plasmid pGB3631, a derivative of the Streptococcus agalactiae plasmid pIP501.
Gene 142: 155-156 (1994) 

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9. S. Brantl,  E. Birch-Hirschfeld, and D. Behnke. RepR protein expression on plasmid pIP501 is controlled by an antisense RNA-Mediated transcription attenuation mechanism.
J. Bacteriol. 175: 4052-4061 (1993) 

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8. S. Brantl, and D. Behnke. Characterization of the minimal origin required for replication of the streptococcal plasmid pIP501 in Bacillus subtilis.
Mol. Microbiol. 6: 3501-3510 (1992) 

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7. S. Brantl, and D. Behnke: The Amount of RepR Protein Determines the Copy Number of Plasmid pIP501 in B. subtilis.
J. Bacteriol. 174: 5475-5478 (1992) 

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6. S. Brantl, and D. Behnke: Copy number control of the streptococcal plasmid pIP501 occurs at three levels.  
Nucleic Acids Res. 20: 395-400 (1992)

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5. S. Brantl, B. Nuez, and D. Behnke: In vitro and in vivo analysis of transcription within the replication region of plasmid pIP501.
Mol. Gen. Genet. 234: 105-112 (1992)

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4. Gentechnologische Arbeitsmethoden. Ein Handbuch experimenteller Techniken und Verfahren. Herausgeber: Rudolf Hagemann (1990). Akademie-Verlag Berlin. Kapitel 1.3., 2.3., 2.8. und 2.11. von S. Brantl und K. Fritzsche.

3. S. Brantl, D. Behnke, and J. C. Alonso: Molecular analysis of the replication region of the conjugative Streptococcus agalactiae plasmid pIP501 in Bacillus subtilis. Comparison with plasmids pAMβ1 and pSM19035.  
Nucleic Acids Res. 18: 4783-4790 (1990)

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2. S. Brantl, A. Nowak, D. Behnke, and J. C. Alonso: Revision of the nucleotide sequence of the Streptococcus pyogenes plasmid pSM19035 repS gene.
Nucleic Acids Res. 17: 10110 (1989)

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1. S. Brantl, M. A. Eldarov, H. Rößler, B. Drescher, H. Lang, S. Rosenthal. K. G. Skryabin: Expression of env Sequences of the Bovine Leukemia Virus (BLV) in the Yeast Saccharomyces cerevisiae.
Yeast 4: 47-59 (1988)

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