Arbeitsplatz Bioinformatik

Prof. Dr. Stefan Schuster

Chair of Bioinformatics
Phone
+49 3641 9-46450
Fax
+49 3641 9-46452
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Curriculum vitae Show content

1981-1986: Undergraduate studies in Biophysics at Humboldt University, Berlin

1986-1988: Graduate studies in Theoretical Biophysics at Humboldt University, Berlin
(Supervisor: Professor Reinhart Heinrich)

1988: PhD thesis entitled "Theoretical studies on the interrelation between time hierarchy in enzymatic reaction systems and optimization principles." For this thesis, I was awarded the degrees of both Dr. rer. nat. and Dr. sc. nat.

1988-1991: Postdoc at Humboldt-University, in the group of Reinhart Heinrich

September 1991-November 1992: Postdoc at the Université Bordeaux II, in the group of Professor Jean-Pierre Mazat

December 1992-March 1993: Postdoc at the Netherlands Cancer Institute, in the group of Dr. Hans Westerhoff

May 1993-April 1997: Senior scientist and lecturer in Biophysics at Humboldt-University, in the group of Reinhart Heinrich

1996: Appointment as a "Privat-Dozent" (Reader) in Theoretical Biophysics

May 1997-April 2003: Scientist at the Max Delbrück Center, Berlin-Buch, still teaching at Humboldt University

August-October 1997: Visiting scientist at the University of Maribor (Slovenia), Dept. of Physics, in the group of Professor Milan Brumen

August 1998-April 2003: Funding by a Heisenberg grant of the DFG

November/December 1998: Working visit at Stuttgart University, Institute of Bioengineering

Since May 2003: Head of the Chair of Bioinformatics at the Faculty of Biology and Pharmacy, Friedrich Schiller University Jena

2008-2014: Member of the Scientific Advisory Board of the Max Planck Institute of Molecular Plant Physiology, Golm

Since 2008: Co-spokesman of the Jena Centre for Bioinformatics

Publications Show content

All publications from Prof. Schuster since 1987:

http://hades.bioinf.uni-jena.de/LitDB/php/pubindex.php

Short selection of research articles:

P. Sieber, M. Platzer, S. Schuster
The definition of open reading frame revisited
Trends in Genetics 34, 2018, 167-170
bibtex | abstract |  doi  ]

S. Schuster
A new solution concept for the ultimatum game leading to the Golden Ratio
Scientific Reports 7, 2017, 5642
bibtex | abstract |  doi  ]

S. Schuster, M. Fichtner, S. Sasso
Use of Fibonacci numbers in lipidomics - Enumerating various classes of fatty acids
Scientific Reports 7, 2017, 39821
bibtex | abstract |  doi  ]

S. Pande, H. Merker, K. Bohl, M. Reichelt, S. Schuster, L.F. de Figueiredo, C. Kaleta , C. Kost
Fitness and stability of obligate cross-feeding interactions that emerge upon gene loss in bacteria
ISME Journal 8, 2014, 953–962
bibtex |  doi  ]

K. Schmeisser, J. Mansfeld, D. Kuhlow, S. Weimer, K. Zarse, S. Priebe, I. Heiland, M. Birringer, M. Groth, A Segref, C. Werner, S. Schmeisser, S. Schuster, A. Pfeiffer, R. Guthke, M. Platzer, T. Hoppe, H. Cohen, D. Sinclair, M. Ristow
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
Nature Chemical Biology 9, 2013, 693-700
bibtex |  doi  ]

F. Wessely, M. Bartl, R. Guthke, P. Li, S. Schuster, C. Kaleta
Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs.
Molecular Systems Biology 7, 2011, 515
bibtex | abstract |  doi  |  url  |  PudMed-ID: 21772263 ]

A. Rezola, L. F. de Figueiredo, M. Brock, J. Pey, A. Podhorski, C. Wittmann, S. Schuster, A. Bockmayr, F.J. Planes
Exploring metabolic pathways in genome-scale networks via generating flux modes.
Bioinformatics 27 (4), Feb, 2011, 534-540
bibtex | abstract |  doi  |  PudMed-ID: 21149278 ]

S. Schuster, T. Pfeiffer, D.A. Fell
Is maximization of molar yield in metabolic networks favoured by evolution?
Journal of Theoretical Biology 252, 2008, 497-504
bibtex | abstract |  PudMed-ID: 18249414 ]

A. von Kamp, S. Schuster
Metatool 5.0: fast and flexible elementary modes analysis
Bioinformatics 22, 2006, 1930-1931
bibtex | abstract |  pdf  |  PudMed-ID: 16731697 ]

J.A. Papin, J. Stelling, N.D. Price, S. Klamt, S. Schuster, B.O. Palsson
Comparison of network-based pathway analysis methods.
Trends in Biotechnology 22, 2004, 400-405
bibtex | abstract |  PudMed-ID: 15283984 ]

J. Stelling, S. Klamt, K. Bettenbrock, S. Schuster, ED. Gilles
Metabolic network structure determines key aspects of functionality and regulation.
Nature 420 (6912), 2002, 190-193
bibtex |  PudMed-ID: 12432396 ]

S. Schuster, M. Marhl, T. Höfer
Modelling of simple and complex calcium oscillations. From single-cell responses to intercellular signalling.
European Journal of Biochemistry 269, 2002, 1333-1355
bibtex |  doi  |  PudMed-ID: 11874447 ]

S. Schuster, T. Pfeiffer, F. Moldenhauer, I. Koch, T. Dandekar
Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniae
Bioinformatics 18, 2002, 351-361
bibtex | abstract |  PudMed-ID: 11847093 ]

S. Schuster, C. Hilgetag, J.H. Woods, D.A. Fell
Reaction routes in biochemical reaction systems: algebraic properties, validated calculation procedure and example from nucleotide metabolism
Journal of Mathematical Biology 45, 2002, 153-181
bibtex | abstract |  doi  |  PudMed-ID: 12181603 ]

T. Pfeiffer, S. Schuster, S. Bonhoeffer
Cooperation and competition in the evolution of ATP-producing pathway
Science 292, 2001, 504-507
bibtex | abstract |  PudMed-ID: 11283355 ]

S. Schuster, DA. Fell, T. Dandekar
A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks
Nat Biotechnol 18, 2000, 326-332
bibtex | abstract |  PudMed-ID: 10700151 ]

S. Schuster, T. Dandekar, D.A. Fell
Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering
Trends in Biotechnology 17, 1999, 53-60
bibtex | abstract |  doi  |  PudMed-ID: 10087604 ]

S. Schuster, D. Kahn, H.V. Westerhoff
Modular analysis of the control of complex metabolic pathways
Biophysical Chemistry 48, 1993, 1-17
bibtex | abstract |  PudMed-ID: 8257764 ]

Editorial Board Show content

2000-2008 Associate editor and since 2009 one of the editors of the journal BioSystems.

BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to
synthesize artificial systems that capture essential principles of natural biological information processing.

Teaching Show content

A large number of topics in the study programme of biophysics from 1985 - 2003, e.g. General Biophysics, Biological Thermodynamics, Biological Systems Theory, Classical Mechanics, and Hydrodynamics. Moreover, I gave lecture series on "Modelling of Biochemical Reaction Systems" at Stuttgart University and the Max Planck Institute in Magdeburg. Since I work at Jena University, I give classes in "Introduction to Bioinformatics", ""Metabolic and Regulatory Networks",  "3D Structures in biological Macromolecules" and " Optimality Principles in Evolution".

See: https://www.schleiden.uni-jena.de/Bioinformatik_Lehre.html (in german)

Research Show content
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