Research at the Matthias Schleiden Institute is done in the spirit of Schleiden: with a focus on cells, in an interdisciplinary way and questioning dogmas.
In the areas of General and Molecular Botany, research at the institute is done on light-regulated processes and the circadian clock in the unicellular green alga Chlamydomonas reinhardtii and on the secondary metabolism of algae and their interactions with bacteria, among other topics. In Plant physiology, the symbiosis between plants and fungi under normal and stress conditions are in the focus. Genetic research in the institute deals with transcription factors controlling flower development, with mechanisms of gene regulation in Bacillus subtilis and other topics. Bioinformatics studies include mathematical modelling and computer simulation of biological processes such as metabolism and host-pathogen interactions.
Numerous projects have an interdisciplinary character, for example, the mathematical description of the complexity of fatty acids and polyketides, computer simulation of circadian rhythms and of the nitrogen metabolism in algae or the application of game theory in molecular and cell biology.